Small Cell Neuroendocrine Carcinoma of the Nasal Cavity: A Case Report / 대한이비인후과학회지

ABSTRACT

Small cell neuroendocrine carcinomas of the sinonasal tract are extremely uncommon tumors, and they have been recognized as a highly aggressive neoplasm with poor prognosis. The authors experienced a case of small cell neuroendocrine carcinoma of nasal cavity in a 72-year old male patient. Histopathologic findings showed a high nucleo/cytoplasmic ratio, and the nuclei were round or oval and hyperchromatic. Immunohistochemical study showed small cell neuroendocrine carcinoma. The chest X-ray and CT scan of chest showed no evidence of primary lung lesion. The patient received chemotherapy, but died from cerebral infarction and its complication. We report our case with a brief review of the literatures.