Clinical comparison between double primary carcinoma of ovary or endometrium and ovarian metastasis in endometrial cancer / 肿瘤研究与临床

ABSTRACT

Objective To investigate the clinical and pathologic features, and prognosis of patients with double primary carcinoma of ovary or endometrium and ovarian metastasis in endometrial cancer. Methods The clinical pathological data of 23 female patients with double primary carcinoma of ovary or endometrium (group A), and 25 female patients with ovarian metastasis in endometrial cancer (group B) from Shanxi Province Tumor Hospital from January 2008 to January 2015 were analyzed retrospectively. Chi-square test was used to compare the count data. Results The results showed significant differences in the morbidity before and after menopause, the primal symptom, the type and grade of pathology, the invasion of myometrium, seroperitoneum and lymphatic metastasis between the two groups (P< 0.05). There was no significant difference in CA125, HE4 and involvement of cervix (P>0.05). There was no obvious advantage of CA125 and HE4 in identifying the double primary carcinoma of ovary or ovarian metastasis in endometrial cancer (P> 0.05). The significant difference was not found in the involvement of cervix of both groups. Conclusions The significant difference in the clinical and pathologic features between the two groups plays a key role in the preoperation diagnosis and treatment guiding . The prognosis of double primary carcinoma of ovary or endometrium is better than that of ovarian metastasis in endometrial cancer.