Regulatory elements in gene circuits:research progress / 军事医学

ABSTRACT

Promoters, terminators, riboswitches and ribosome-related sequences are involved in gene expression regulation at transcription and translation levels to achieve precise expression of the target gene .As regulatory elements of genes, they are widely used in the construction of gene circuits and play important roles in genome engineering and metabolic engineering.This paper not only summarized the structural characteristics of the common gene regulatory elements, the mechanism of action and modification , but expounded the function of natural and artificial gene regulatory elements in the optimization of metabolic pathways , and the future construction of gene circuits and applications .