Development of Multiplex Immunoassay Based on Inductively Coupled Plasma Mass Spectrometry / 分析化学
Chinese Journal of Analytical Chemistry
; (12): 1786-1794, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-663555
Responsible library:
WPRO
ABSTRACT
Immunoassay is of great importance in the field of clinical detection. Our group proposes the inductively coupled plasma mass spectrometry ( ICP-MS) based immunoassay. Multiplex immunoassay can be realized by stable isotope tagging strategy combined with ICP-MS detection. Since then, large amount of researches in this field have been made at home and abroad, and the method has been proved applicable to the analysis of biological small molecules, proteins, nucleic acids and cells. In this article, the history and development of immunoassay, the characters of ICP-MS based immunoassay, single component and multiplex immunoassay, and the magnetic immunoassay that is recently fast developed are reviewed. The prospect of the developing tendency is also anticipated, hoping to provide references for the research in this field.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Analytical Chemistry
Year:
2017
Document type:
Article