Progress in arsenic carcinogenesis / 中华地方病学杂志
Chinese Journal of Endemiology
; (12): 933-936, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-665721
Responsible library:
WPRO
ABSTRACT
Arsenic is one of the chemical pollutants,which is widely distributed in natural environment.International agency for research on cancer (IARC) has made it clear that arsenic and its compounds are carcinogens;endemic arseniasis has become a public health problem that seriously endangers human health.However,the arsenic metabolic and toxic effects of the species vary widely,failure to replicate a suitable carcinogenic model on animals,and there is no recognized carcinogenic mechanism.The author provide a brief review of arsenic metabolism,arsenic genotoxicity,arsenic-induced epigenetic changes,arsenic-induced changes in cell signaling pathways,arsenic and estrogen receptor expression,and arsenic immunotoxicity,to provide a reference for control and prevention of endemic arseniasis.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endemiology
Year:
2017
Document type:
Article