Regulatory role of microRNA in allergic disease in children / 中国医师进修杂志

ABSTRACT

MicroRNA is small,noncoding,single-stranded RNA,which represses gene expression by mRNA destabilization and translational inhibition.With the further study of microRNA,it is found to be related to allergic disease in children, including allergic rhinitis, atopic dermatitis, eosinophilic esophagitis,asthma,milk protein allergy,etc.In recent years,with the change of the living environment and diet structure,the incidence of children allergic disease is increasing.The emergence of microRNA provides a new diagnosis method for children allergic disease.This article summarizes the research progress of microRNA in allergic disease in children.