Analysis of Incidence Rate and Related Factors of Thyroid Nodules / 医学研究杂志

ABSTRACT

Objective To investigate and analysis the incidence rate and related factors of thyroid nodules in urban and rural health population in Heilongjiang Province.Methods A cross-sectional survey was conducted using stratified cluster random sampling.Carried on the random questionnaire survey,general physical examination and thyroid ultrasonography,collected blood and urine samples;The incidence of thyroid nodules was determined by ultrasound.Results The incidence of thyroid nodules in urban and rural of Heilongjiang Province was 27.77％ and 18.18％,(x2 =33.991,P ＜ 0.01).women were higher than men.The incidence of thyroid nodules was significantly increased with the increase of age,(P ＜ 0.01).In addition,urinary iodine,TSH level,TPOAb,TgAb,systolic blood pressure,fasting blood glucose,triglyceride,cholesterol,low density lipoprotein and high density lipoprotein were significantly higher in patients with thyroid nodules than normal population(P ＜ 0.05).Logistic multivariate analysis showed that geographical distribution,gender,age,cholesterol levels and glycosylated hemoglobin were independent risk factors for the incidence of thyroid nodules (P ＜ 0.05),among which the influence of geographical distribution was found for the first time in Heilongjiang region.Conclusion The incidence of thyroid nodules in the urban was significantly higher than that of the rural in Heilongjiang Province,women were higher than men.The incidence of thyroid nodules was significantly higher with age.Geographical distribution gender,age,cholesterol and glycosylated hemoglobin level are independent risk factors for the incidence of thyroid nodules.