Anti-colon cancer property of anthocyanins:research advances / 国际药学研究杂志

ABSTRACT

The global incidence and mortality of colon cancer have significantly increased in recent years. Surgical therapy of colon cancer is difficult and colon cancer cells have strong metastatic capability. Because anticancer chemotherapy drugs are of high toxicity,the use of plant extracts has unique advantage in preventing and treating colon cancer. Anthocyanins are the natural water-sol-uble glycosidic pigments,the basic colors of red/purple fruits and vegetables and main flavonoids in daily dietary intake. Anthocyanins have been well documented to exert tumor suppressive effects on the occurrence and progression of colon cancer. This review aims to provide the up-to-date status of research on anthocyanins and colon cancer,speculate the molecular mechanisms,the anti-colon can-cer property of anthocyanins,and give the prospect of the potential clinical uses of anthocyanins.