An experimental study on the cerebral vascular injury in case of positional asphyxia / 中国法医学杂志

ABSTRACT

Objective This research aimed to study if the cerebral vascular injury can be caused by the positional asphyxia. Method The brain tissue sections were studied immunohistochemically (SABC method) by using the anti-human von Willebrand Factor (vWF) and anti-human albumin as the first antibody. Results No positive expression of vWF and albumin was found in the cerebral blood vessels of control group. The vivid positive expression of albumin and vWF were observed in the positional asphyxia group. Conclusion The results indicate that the positional asphyxia can result the expression of the vWF in the cerebral vessels and it seems one of the injury markers in the cerebral blood vessels and can be used to probe the mechanism of positional asphyxia.