The development of a bioartificial liver and its application in acute liver failure patients / 中国普通外科杂志
Chinese Journal of General Surgery
; (12)2001.
Article
in Zh
| WPRIM
| ID: wpr-673761
Responsible library:
WPRO
ABSTRACT
Objective Using polysulfon fibers, a new bioartificial liver was developed. This study was to evaluate the efficacy of this bioartificial liver in the support of a disfunctioned liver. Methods Hepatocytes were procured from swine using Seglen′s methods. The bioartificial liver was constructed based on polysulfon bioreactor with a procurement of 10 10 hepatocytes, and was applied in 12 acute liver failure patients for 14 sessions. Each BAL treatment lasted 6 hours. The general conditions of the patients and the biochemical parameters were evaluated. Results After treatment with bioartificial liver, ammonia, prothrombin time and total bilirubin level significantly decreased (all P
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of General Surgery
Year:
2001
Document type:
Article