Expression of tansforming growth factor-? and tansforming growth factor-? receptor in colorectal adenocarcinoma / 中国癌症杂志

ABSTRACT

Purpose:To investigate the relationship between the expression tansforming growth factor ?(TGF ?) and the differentiation, invasion of colorectal adenocarcinoma.Methods:To observe the expression of transforming growth factor ? and transforming growth factor ? receptor in 68 samples of colorectal adenocarcinoma with immunohistochemical technique. Results:The cells with positive reaction of TGF ? antibody were scattered in the stroma. The cells with infiltrative growth had positive TGF ? staining.Conclusions:It was indicated that TGF ? might play an important role in the invasion and metastasis of colorectal adenocarcinoma.