Liver cirrhosis leads to poorer survival in patients with end-stage renal disease
The Korean Journal of Internal Medicine
; : 730-738, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-67607
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS:
Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mortality betweentwo dialysis modalities.METHODS:
Adult patients (≥ 18 years of age) starting dialysis for ESRD were enrolledin the present study from 2000 to 2011. We analyzed 1,069 patients withESRD; of these, 742 patients were undergoing hemodialysis (HD) and 327 patientswere undergoing peritoneal dialysis (PD).RESULTS:
The prevalence of LC was 44 of 1,069 patients (4.1%). The cumulative 1-,3-, and 5-year survival rates of noncirrhotic patients were 93%, 83%, and 73%, respectively,whereas the equivalent survival rates of cirrhotic patients were 90%,68%, and 48%, respectively (p = 0.011). After adjustment, LC was an independentrisk factor for death in patients with ESRD. No difference in mortality associatedwith LC was found between the HD and PD subgroups.CONCLUSIONS:
Of the patients with ESRD, cirrhotic patients had poorer survivalthan noncirrhotic patients. Among patients with ESRD and LC, survival of patientsundergoing PD may be comparable with that of patients undergoing HD.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Chronic Kidney Disease
/
Cirrhosis
/
Digestive System Diseases
/
Kidney, Renal Pelvis and Ureter Cancer
Database:
WPRIM (Western Pacific)
Main subject:
Prevalence
/
Survival Rate
/
Mortality
/
Renal Dialysis
/
Peritoneal Dialysis
/
Dialysis
/
Kidney Failure, Chronic
/
Liver
/
Liver Cirrhosis
Type of study:
Prevalence study
/
Prognostic study
Limits:
Adult
/
Humans
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2016
Document type:
Article