Insulin resistance of islet ?-cells / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12)1985.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-676329
Responsible library:
WPRO
ABSTRACT
It has been proved recently that insulin signal transduction pathway and insulin resistance exist in islet?-cells.Defects in insulin signaling of the?-cells decrease glucose-stimulated first-phase insulin release, inhibit proliferation of?-cells and promote apoptosis of?-cells.Obesity accelerates the development of insulin resistance of?-cells,which may play a central role in the pathogenesis of type 2 diabetes mellitus.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
1985
Document type:
Article