Tissue microarray in studying difference of cell proliferation and microvessel density between hepatic malignant and benign lesions / 第二军医大学学报
Article
in Zh
| WPRIM
| ID: wpr-678077
Responsible library:
WPRO
ABSTRACT
Objective: To study the difference of the cell proliferation activity and microvessel density (MVD) between hepatic benign and malignant lesions for further demonstrating the biological features of tumor. Methods: There were 290 specimens of hepatocellular carcinoma (HCC), 128 specimens of cirrhosis tissues and 25 specimens of hepatic benign lesions were detected for PCNA, Ki 67 and MVD by immunohistochemistry on tissue microarray, respectively.Results: The expression level of PCNA and Ki 67 in HCC were 90.2% and 43.1%, which was obviously higher than that in cirrhosis (48.5% and 3.9%, P 0.05). MVD counting in HCC pathological grade Ⅰ Ⅱ(29.9?18.6) was higher than those in gradeⅢ (22.2? 18.2) and Ⅳ(22.9?19.0, P
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Academic Journal of Second Military Medical University
Year:
1982
Document type:
Article