MITOCHONDRIAL DNA MICROSATELLITE INSTABILITY AND EXPRESSION OF Bcl-2 AND Bax mRNA IN GASTRIC CANCER AND ITS PRECANCEROUS LESIONS / 解放军医学杂志
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-678639
Responsible library:
WPRO
ABSTRACT
Objective To explore the relationship between mitochondrial DNA microsatellite instability(mtMSI) and expression of Bcl 2 and Bax mRNA in gastric cancer and its precancerous lesions. Methods mtMSI and expressions of Bcl 2 and Bax mRNA were detected with PCR SSCP and RT PCR. Results Expressions of Bcl 2 mRNA in intestinal metaplasia (IM,53 3%) and dysplasia (Dys, 70%) were significantly higher than that in normal control(10%, P
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Medical Journal of Chinese People's Liberation Army
Year:
2001
Document type:
Article