Study on the changes of indirect biliburin in obstructive sleep apnea hypopnea syndrome before and after continuous positive airway pressure ventilation / 中国呼吸与危重监护杂志

ABSTRACT

Objective To investigate the changes of plasma indirect bilirubin(IDB) and its role in the pathogenesis of obstructive sleep apnea hyponea syndrome(OSAHS).Methods Plasma IDB levels were detected in 30 healthy controls and 20 patiemts with OSAHS by improved J G method with 7170A automatic biochemistry analytical apparatus.Plasma IDB levels in OSAHS were compared before and an overnight or a month after CPAP treatment.ResultsPlasma IDB levels in controls were significantly higher than those in OSAHS [(16 2?5 0) ?mol/L vs (8 0?3 5)?mol/L, P 0 05] and markedly increase after a month CPAP ventilation [(8 0?3 5) ?mol/L vs (14 0?5 0)?mol/L, P