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Effects of scorpion venom active peptides on platelet aggregation, thrombosis in carotid artery and plasma 6-keto-PGF_(1?) and TXB_2 in rabbits and rats / 中成药
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-681792
Responsible library: WPRO
ABSTRACT

Objective:

To investigate the mechanism of scorpion venom active peptides(SVAPs) on platelet aggregation.

Methods:

Platelet aggregation in vivo and vitro was determined by turbidimetry. Carotid thrombosis model was induced by electrostimulation. The determination of 6 keto PGF 1 and TXB 2 were performed by radioimmunoassay.

Results:

SVAPs 0.125,0.25,0.5mg?ml -1 significantly inhibited the rabbit platelet aggregation triggered by thrombase 0.03u.ml -1 , ADP 10u.ml -1 in vitro( P

Full text: Available Database: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Traditional Patent Medicine Year: 1992 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Traditional Patent Medicine Year: 1992 Document type: Article
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