A Case of POEMS Syndrome Associated with Sarcoidosis / 대한내과학회지
Korean Journal of Medicine
; : 107-112, 2012.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-68206
Responsible library:
WPRO
ABSTRACT
POEMS syndrome is a monoclonal plasma cell disorder characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. Pulmonary manifestations of POEMS syndrome are common, with frequent symptomatic and asymptomatic respiratory involvement on presentation. However, there have been no reported cases of concomitant sarcoidosis and POEMS syndrome. We treated a 55-year-old woman who presented with dyspnea and bilateral lower leg pitting edema. She had been diagnosed with sarcoidosis 4 years earlier. We reassessed the patient meticulously and found polyneuropathy, IgG lambda type monoclonal gammopathy, lymphadenopathy, hepatosplenomegaly, hypothyroidism, hypertrichosis, and pleural and pericardial effusions, all of which led us to diagnose POEMS syndrome. Immunosuppression with high-dose dexamethasone led to clinical and radiological improvement.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Paraproteinemias
/
Pericardial Effusion
/
Plasma Cells
/
Polyneuropathies
/
Sarcoidosis
/
Skin
/
Immunoglobulin G
/
Dexamethasone
/
Immunosuppression Therapy
/
POEMS Syndrome
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2012
Document type:
Article