Studies on anti-ageing effect of elk antlers ethanolic fluidextracr / 中成药

ABSTRACT

AIM: To study the anti ageing effect of elk antlers ethanolic fluidextract. METHODS: The subacute ageing model mice induced by D galactose was established and was given elk antlers ethanolic fluidextract for 30 days. SOD and MDA activity of the blood in the mice was determined at the end of experiment. The anti stress action and the immunomodulation were measured by determining the surviving time under hypoxic condition and swimming time and by determining the immune organ index, respectively. RESULTS: Elk antlers ethanolic fluidextract could raise SOD activity and reduce MDA content of the blood in subacute ageing model mice. It could prolong the surviving time under hypoxic conditon and swimming time in mice. It could also increase spleen index and reduce thymus index in mice. CONCLUSION: Elk antlers ethanolic fluidextract has anti oxidation action. It can strengthen the ability to bear hypoxic condition and tiredness in mice.It has certain action to regulate immune function.