ISOLATION OF AN ESTERASE PRODUCER TRICHOSPRONBRASSICAE AND ITS CATALYTIC PERFORMANCE IN KINETICRESOLUTION OF KETOPROFEN / 微生物学通报
Microbiology
; (12)1992.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-683969
Responsible library:
WPRO
ABSTRACT
A strain of yeast capable of hydrolyzing ethyl ester of racemic Ketoprofen with high enantioselectivity has been isolated from soil after two-step enrichment. The yeast was identified as Trichosporon brassicae. The process of growth and enzyme production was investigated. The catalytic performance of the resting cell of KET4 in kinetic resolution of Ketoprofen was also investigated. When the conversion of substrate reached 41% , enantiomeric excess of the (S) - Ketoprofen produced was 91 % , indicating a high enantiomeric ratio of 45.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Microbiology
Year:
1992
Document type:
Article