Effects of pinacidil on intracellular free calcium concentration of cultured neonatal rat cardiomyocytes during hypoxia/reoxygenation / 医学研究生学报
Journal of Medical Postgraduates
; (12)2003.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-684220
Responsible library:
WPRO
ABSTRACT
Objectives:
To examine effects of pinacidil on intracellular free calcium concentration of cardiomyocytes during hypoxia/reoxygenation.Methods:
A cell culture model of neonatal rat cardiac myocytes was used. There were three groups, including control group, hypoxia/reoxygenation group and pinacidil group. Confocal microscope was used with Fluo 3/AM as calcium indicator to detect changes of intracellular free calcium concentration.Results:
The intracellular fluoresence intensity of singular cardiomyocyte in hypoxia/reoxygenation group was significantly higher than that of the controls( P
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2003
Document type:
Article