Bacteriophage Lysins:A Novel Effective Antibacterial Agents / 微生物学通报
Microbiology
; (12)2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-686445
Responsible library:
WPRO
ABSTRACT
Lysins are efficient bacteria cell wall digesting enzymes encoded by DNA bacteriophage. Gram-positive bacteriophage lysins feature similar domain structure, high lytic efficiency, synergic antibacterial effect with antibiotics, rare neutralization by antibodies, less chance of developing drug-resistant strains, et al. The past decade has seen a considerable amount of research worldwidely focused on lysin, and lysins have been used successfully in a variety of animal models to control pathogenic antibiotic resistant bacteria found on mucosal surfaces and infected tissues. The great potential of lysins as an anti-infective agent prompted this review.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Microbiology
Year:
2008
Document type:
Article