Calcitonin gene-related peptide and lung diseases / 国际儿科学杂志

ABSTRACT

Pulmonary diseases include infection,injury,asthma,interstitial disease,tumor,hypertension and so on.The mechanisms are not fully understood.Calcitonin gene-related peptide(CGRP),a 37-amino acid neuropeptide,identified in multiple species,has widespread distribution and expression.Although there are no cases that CGRP works in pulmonary disease,many studies have showed that CGRP play an important role on cell line in vitro or on animal models.This brief review provides a preliminary understanding of the diverse biological effects of CGRP and its antagonist in respiratory system.