Progress of diagnosis and treatment of pediatric non-alcoholic fatty liver disease / 国际儿科学杂志

ABSTRACT

Non-alcoholic fatty liver disease (NAFLD) refers to a wide spectrum of liver diseases ran ging from simple fatty liver(SFL) to non-alcoholic steatohepatitis(NASH),which in turn can evolve into cirrhosis and end stage of liver disease.With the improvement of living standards,the number of obese children gradually has increased,the detection rate of NAFLD also has showed an growing trend.However,the pathogenesis is still unclear.Auxiliary examinations include biochemical tests,imaging studies and liver biopsy,the last one is the "golden standard" of the diagnosis.The treatments of NAFLD consists of dietary intervention and lifestyle changes,even medical therapies.At present,the awareness of children NAFLD is imperfect,its diagnosis and treatment remain to be further exDlored.