Neuroprotective effect of uric acid in cerebral ischemia-reperfusion injury / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 701-707, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-693057
Responsible library:
WPRO
ABSTRACT
Uric acid is an end product of purine metabolism. A large number of clinical studies have shown that high-level serum uric acid is a good predictor of outcome in patients with acute ischemic stroke. Oxidative stress is the main mechanism of cerebral ischemia-reperfusion injury. As a potent antioxidant, uric acid is considered to have a potential neuroprotective effect in the vascular recanalization treatment, but its specific mechanism remains unclear. This article reviews the neuroprotective mechanism of uric acid in cerebral ischemia-reperfusion injury in order to provide ideas for future research and clinical practice.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2018
Document type:
Article