Changes of peritoneal membrane transport characteristics in continuous ambulatory peritoneal dialysis patients

ABSTRACT

Background: In recent years, Continuous Ambulatory Peritoneal Dialysis (CAPD) has been applied extensively in treating end-stage chronic renal failure. The peritoneal membrane transport characteristics were varied in each patient, dependent on peritoneal anatomical structures. Objective: To determine the peritoneal membrane transport characteristics in continuous ambulatory peritoneal dialysis patients and its changes after 6-month treatment. Subjects and method: The descriptive prospective study was performed on 44 CAPD patients using the Peritoneal Equilibration Test (PET) to evaluate the peritoneal membrane transport characteristics. Results: 44 patients (19 men and 25 women), age 42.8 +/- 13.5 years, mean body mass index 19.5 +/- 2.1. PET at the 1st month (M1) and 6th month (M6) showed that the high-moderate level of peritoneal membrane transport characteristics are prevalent (50% of patients), high 27.3%, low-moderate 18.2% and low 5%. After 6 months of CAPD, the peritoneal membrane transport characteristics, mean values of PET, ultrafiltration, lost of protein \u2026 were unchanged. Conclusions: The high-moderate levels of peritoneal membrane transport characteristics are prevalent; this is a good type for CAPD about urea, creatinine clearance and ultrafiltration. The peritoneal membrane transport characteristics directly affected some of the clinical indexes ultrafiltration, processing lost prorein through filtrated fluid, blood protein and albumin levels\u2026