Role of cell death mechanism in viral myocarditis / 中华实用儿科临床杂志

ABSTRACT

Viral myocarditis is a nonspecific myocardial inflammation caused by viral infection,10％ - 20％ of them can develop to dilated cardiomyopathy eventually. Virus infections caused direct myocardial damage as they at-tack. Persistent inflammation and persistent virus infections induced an immune inflammation response and eventually caused indirectly damage,leading to further harm to myocardia. Different forms of cell death including apoptosis,autoph-agy,necrosis and necroptosis were associated with myocarditis. The role and mechanism of different cell death in the development of viral myocarditis will be described.