Diagnosis and treatment of Diamond-Blackfan anemia / 中华实用儿科临床杂志

ABSTRACT

Diamond-Blackfan anemia is a rare inherited bone marrow failure syndrome,characterized by sim-plered hematopoietic failure,usually macrocytic anemia with an absence or less than 0.05 of erythroid precursors (erythroblastopenia)in an otherwise normal bone marrow.Patient management is therefore centered on accurate diagno-sis,appropriate use of transfusions and iron chelation,corticosteroids,Cyclosporine A and hematopoietic stem cell trans-plantation.