Feasibility study of low tube voltage and current on brain CT perfusion / 实用放射学杂志

ABSTRACT

Objective To investigate the feasibility of 80 kV and low tube current on brain CT perfusion(CTP).Methods Sixty patients underwent 80 kV CTP examination,and were randomly divided into five groups according to different tube currents,A group (40 mAs),B group (60 mAs),C group (80 mAs),D group (100 mAs),E group (150 mAs).Twelve patients in each group were selected to analyze the parameters of the caudate nucleus and white matter frontals and temporal,including CBV,CBF and MTT.Subjective image quality,CT value,SD,SNR,CNR and radiation dose were measured and calculated in the 5 groups respectively.Results Differences of CBV and CBF in the caudate nucleus and white matter frontals were existed among A group,B group,and E group (P＜0.05).There were no significant differences of CT value among the 5 groups (P＞0.05).For the SD and SNR,E group was better than A-D groups (P＜0.05).The CNR was higher in E group than that in A group (P＜0.05).The subjective image quality score evaluation in C,D groups were not lower than that in E group(P ＞0.05).The ED of A-D groups were all lower than that of E group (P＜0.05).Conclusion 80 kV/80 mAs brain CTP can obtain accurate perfusion parameter and satisfied image quality,and the radiation dose can be reduced by 46.22％ (2.42 mSv).