Diagnosis and treatment progression of pigmented villonodular synovitis of ankle joint / 医学研究生学报

ABSTRACT

Pigmented villonodular synovitis of ankle joint is an uncommon bone and joint disease in clinic. Because of its oc-cult onset,slow progression and the the lack of typical characteristics at the early stage of the disease,thus,being clinically prone to misdiagnosis. The etiology and pathogenesis of this disease has not yet fully elucidated. However,according to literatures reported that there are inflammatory reactions, lipid metabolism disorders, trauma, genetic factors and tumor theory. At present, the treatment of pigmented villonodular synovitis of ankle joint has not yet stereotypes,while the medical community has not yet reached a consensus on its treatment. This article systematicly reviews the etiology and pathogenesis,pathological features,imaging findings,clinical manifes-tations and the latest treatment progress of ankle igmented villonodular synovitis.