Cytogenetic Aberration Analysis of Midtrimester Amniotic Fluid / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
; : 1040-1044, 2002.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-70091
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To analyze cytogenetic results of prenatal genetic amniocentesis.METHODS:
From January 1997 to December 2000, We analyzed 1,390 cases of midtrimester amniocentesis which were done at Gil medical center of Gachon medical school according to its indications and maternal age.RESULTS:
Chromosomal aberrations were found in 88 cases (6.3%). Of all our chromosomal aberrations, 29 cases (2.1%) of normal variants and 59 cases (4.2%) of abnormal karyotypes were found. 37 cases of autosomal numerical abnormal karyotypes and 7 cases of sex chromosomal abnormal karyotypes were diagnosed. In abnormal karyotype group, the incidence was high after 40 years of maternal age and in abnormal ultrasound findings, but no such correlations were found in normal variant group.CONCLUSION:
In analysis of midtrimester amniocentesis, it would be better to analyze separately abnormal karyotype group and normal variant group.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pregnancy Trimester, Second
/
Schools, Medical
/
Incidence
/
Chromosome Aberrations
/
Ultrasonography
/
Maternal Age
/
Cytogenetics
/
Abnormal Karyotype
/
Amniocentesis
/
Amniotic Fluid
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2002
Document type:
Article