Risk factors of pulmonary hemorrhage in patients undergoing CT-guided percutaneous lung biopsy / 中国介入影像与治疗学

ABSTRACT

Objective To explore the risk factors of pulmonary hemorrhage in patients undergoing CT-guided percutaneous lung biopsy.Methods Data of 347 patients who underwent CT-guided percutaneous lung biopsy were retrospectively reviewed.Clinical factors that might cause pulmonary hemorrhage,including age,gender,whether combine with emphysema,main pulmonary artery diameter,and whether or not taking antiplatelet drugs,puncture frequency,needle angle,maximum diameter,morphology,as well as the distance between lesion and pleural were analyzed.Results Among 347 patients,168 patients developed pulmonary hemorrhage after the procedures (hemorrhage group),including 25 patients with hemoptyses and 1 patient with hemopneumothorax.Compared with non hemorrhage group,ratio of female (P＝0.010),of emphysema (P＝0.016) and of sub-solid lesions (P＝0.036) were higher in hemorrhage group,while lesions' diameter was smaller (P＝0.003) and ratio of subpleural lesions was lower (P＜0.001) in hemorrhage group.The difference of pulmonary hemorrhage ratio between patients with enlarged main pulmonary artery diameter at CT (≥2.9 cm) or not had no statistical significance (x2 ＝ 0.011,P＝ 0.915).Conclusion Pulmonary hemorrhage after CT-guided percutaneous lung biopsy is common but rarely need clinical treatment.Enlarged main pulmonary artery diameter at CT (≥2.9 cm) is not the risk factor of pulmonary hemorrhage after puncture.