Advances of active ingredients of traditional Chinese medicine in the preven-tion and treatment of osteoarthritis / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 279-285, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-704335
Responsible library:
WPRO
ABSTRACT
Osteoarthritis (OA),a common chronic degenerative joint disease,rises gradually with age,which seri-ously affects the quality of life of middle-aged and elderly patients. Currently,the therapeutic medications such as nonsteroidal anti-inflammatory drugs (NSAIDs)and analgesics might improve OA symptoms,but cannot prevent the development of OA. The active ingredients of traditional Chinese medicine (TCM)have unique advantages in the treatment of OA. This article reviews the research progress of active ingredients of TCM in the prevention and treatment of OA reported by domestic and foreign journals in the past five years from the aspects of inhibition of the secretion of inflammation-related factors,improvement of cartilage matrix synthesis and catabolic imbalance, inhibition of chondrocyte apoptosis,promotion of chondrocyte proliferation,and regulation of estrogen levels,with an attempt to provide a theoretical basis for the development of new drugs for OA.
Full text:
Available
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 9: Noncommunicable diseases and mental health
Database:
WPRIM (Western Pacific)
Aspects:
Patient-preference
Language:
Chinese
Journal:
Journal of China Pharmaceutical University
Year:
2018
Document type:
Article