The progress of pathogenesis and treatment in angioimmunoblastic T-cell lymphoma / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 633-637, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-706863
Responsible library:
WPRO
ABSTRACT
Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common subtypes of peripheral T-cell lymphomas. It is a fol-licular T-helper-derived neoplasm, and characterized by the presence of some genetic alterations, such as mutations in TET2, DN-MT3A, IDH2, and RHOA. Anthracycline-containing regimens represent the most widely adopted first-line option; however, new biolog-ic agents should be designed and incorporated to improve treatment response. The elucidation of the specific roles of these genetic al-terations in AITL will facilitate the development of molecularly targeted therapies to treat this disease.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2018
Document type:
Article