Genotypes of Treponema pallidum subspecies pallidum and their clinical significance / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
; (12): 468-471, 2018.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-711431
Responsible library:
WPRO
ABSTRACT
With the development of genome sequencing technology,Treponema pallidum has been found to have different subspecies all around the world. It is widely recognized that Treponema pallidum could be subtyped by analyzing two or three target genes. Advances in molecular epidemiology of syphilis reveal that clinical characteristics of Treponema pallidum,such as virulence,serofast,drug resistance and the site of in-fection,are related to its subspecies. Specifically,14f/f may be more virulent;serofast may be more likely to happen in patients infected with Treponema pallidum of Tpr i genotype;A2058 and A2059 genes may be re-lated to resistance to macrolides. All these will be summarized in this review.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Microbiology and Immunology
Year:
2018
Document type:
Article