The application value of serological detection of ASCA and ANCA serum level in the diagnosis and treatment of inflammatory bowel disease / 中华检验医学杂志

ABSTRACT

With the updating of the consensus on the diagnosis and treatment of inflammatory bowel disease, ASCA, ANCA and other serological markers are not included as routine examination items , so many related problems need to be recognized .In some special cases , the high specific serological examination still has clinical value in the differential diagnosis for atypical symptom patents .Researches support that ASCA , ANCA and other serological tests have the ability to predict the occurrence of the disease , to evaluate the biological behavior , or to predict clinical response to infliximab and the recurrence after surgery .Finding new methods for combined detection to increase sensitivity and specificity , discovery of new serological antibodies are still research hotspots in the future ."no agreement have been reached about serological detection" in the new consensus is just the expectation of large-scale, multicenter clinical research on serological detection of IBD in China .