Bone Health in Adrenal Disorders
Endocrinology and Metabolism
; : 1-8, 2018.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-713217
Responsible library:
WPRO
ABSTRACT
Secondary osteoporosis resulting from specific clinical disorders may be potentially reversible, and thus continuous efforts to find and adequately treat the secondary causes of skeletal fragility are critical to ameliorate fracture risk and to avoid unnecessary treatment with anti-osteoporotic drugs. Among the hyperfunctional adrenal masses, Cushing's syndrome, pheochromocytoma, and primary aldosteronism are receiving particularly great attention due to their high morbidity and mortality mainly by increasing cardiovascular risk. Interestingly, there is accumulating experimental and clinical evidence that adrenal hormones may have direct detrimental effects on bone metabolism as well. Thus, the present review discusses the possibility of adrenal disorders, especially focusing on pheochromocytoma and primary aldosteronism, as secondary causes of osteoporosis.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Endocrine System Diseases
/
Musculoskeletal Diseases and Rheumatic Disorders
/
Other Malignant Neoplasms
Database:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Pheochromocytoma
/
Mortality
/
Cushing Syndrome
/
Hyperaldosteronism
/
Metabolism
Type of study:
Prognostic study
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2018
Document type:
Article