Early disseminated recurrence after liver resection in solitary hepatocellular carcinoma
Annals of Surgical Treatment and Research
; : 129-134, 2018.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-713272
Responsible library:
WPRO
ABSTRACT
PURPOSE:
Although few hepatectomy patients develop unexpected early diffuse and multinodular recurrence in the remnant liver, the prognosis in such cases is often dismal. The aim of this study was to evaluate the risk factors of early disseminated multinodular hepatocellular carcinoma (HCC) recurrence within 3 months after liver resection for solitary HCC.METHODS:
Eighty-four patients who were diagnosed with recurrent HCC within 3 months after hepatectomy for solitary HCC were retrospectively reviewed. Disseminated HCC recurrence was defined as more than 10 tumors in both lobes and total tumor size >10 cm.RESULTS:
Preoperative α-FP level, incidence of poor tumor grade, and presence of portal vein tumor thrombosis were higher in the patients with disseminated HCC recurrence than in those without disseminated HCC recurrence (P 1,000 ng/dL was a predisposing factor of disseminated HCC recurrence within 3 months after liver resection. The overall survival rate for patients without disseminated HCC recurrence was higher than that for patients with disseminated HCC recurrence (P 1,000 ng/dL. Such patients should be frequently evaluated for the early detection of recurrent HCC for early intervention.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
Portal Vein
/
Prognosis
/
Recurrence
/
Thrombosis
/
Incidence
/
Causality
/
Multivariate Analysis
/
Survival Rate
/
Retrospective Studies
/
Risk Factors
Type of study:
Etiology study
/
Incidence study
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Observational study
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Prognostic study
/
Risk factors
/
Screening study
Limits:
Humans
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2018
Document type:
Article