A Case of Acquired Amegakaryocytic Thrombocytopenia Responding to Immunosuppressive Therapy / 대한혈액학회지
Korean Journal of Hematology
; : 147-152, 2002.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-720543
Responsible library:
WPRO
ABSTRACT
Acquired amegakaryocytic thrombocytopenia is a relatively rare bone marrow failure disorder characterized by severe thrombocytopenia associated with a total absence or a marked reduction in the number of bone marrow megakaryocytes. We report a case of acquired amegakaryocytic thrombocytopenia. A 39-year old man admitted our hospital because of gingival bleeding and purpura on the thigh, his initial complete blood cell counts were white blood cell 5.6 103/micro liter hemoglobin 9g/dL, and platelet 1 103/micro liter On the bone marrow study, megakaryocyte was not observed and cytogenetic analysis of marrow was 46, XY, inv(9). (p11q13). Other autoimmune markers were negative. The patient received steroid therapy during 8 weeks, but there was no significant improvement and then he received immunosuppressive therapy with antithymocyte globulin and cyclosporin-A. Thereafter the platelet count increased to 80 103/micro liter, and this level continued for 10 months
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Platelet Count
/
Purpura
/
Thigh
/
Thrombocytopenia
/
Blood Cell Count
/
Blood Platelets
/
Bone Marrow
/
Megakaryocytes
/
Cytogenetic Analysis
/
Hemorrhage
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Hematology
Year:
2002
Document type:
Article