A Case of Neuroendocrine Carcinoma and Childhood Myelodysplastic Syndrome in Hyper-IgM Syndrome
Korean Journal of Hematology
; : 330-335, 2009.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-721039
Responsible library:
WPRO
ABSTRACT
Congenital immunodeficiency is one or combined immune defect in immunoglobulin, leukocyte, and complement. These patients have increased susceptibility to respiratory infection. Hence, their infection must be taken care of, tried to gene therapy and stem cell transplantation. We present here a case of hyper-IgM syndrome in an 11-year-old male patient who complained of abdominal distension and abdominal pain. Multiple abdominal masses were detected by abdominal computed tomography (CT) and he was diagnosed with neuroendocrine carcinoma by mass biopsy. There was no evidence of metastasis of cancer cells to the bone marrow, but a dysgranulopoietic feature was noted and he was diagnosed with childhood myelodysplastic syndrome. This is the first report that neuroendocrine carcinoma is associated with childhood myelodysplastic syndrome in hyper-IgM syndrome.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Bone Marrow
/
Myelodysplastic Syndromes
/
Complement System Proteins
/
Immunoglobulins
/
Genetic Therapy
/
Abdominal Pain
/
Carcinoma, Neuroendocrine
/
Stem Cell Transplantation
/
Hyper-IgM Immunodeficiency Syndrome
Limits:
Child
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Hematology
Year:
2009
Document type:
Article