Clinical Features and Prognostic Factors of Brain Abscess / 감염과화학요법
Infection and Chemotherapy
; : 235-240, 2003.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-721461
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Brain abscess is a important infectious disease of the central nervous system, although the mortality has been reduced due to new antibiotics therapy and improved imaging techniques. MATERIALS amp;METHODS:
Over a period of 17 years, from March 1986 to Feburary 2003, 110 patients were identified as having brain abscess at the Severance Hospital. Based on medical records, we reviewed these cases and investigated retrospectively the epidemiology, clinical findings, therapeutic modalities and prognostic factors of brain abscess.RESULTS:
There were 78 males and 32 females, and the mean age was 34.4 years. The most common location of brain abscess was the parietal lobe (24.5%), followed by temporal (20.9%) and frontal lobes (20.0%). Gram positive cocci were most frequently isolated as the causative microorganism. Tuberculous brain abscess were diagnosed in 6 (8.8%) cases. The common predisposing conditions were neurosurgery (21.8%), otitis media (10%) and congenital heart disease (8.2%). Headache (63.6%), fever (55.5%) and focal neurologic deficits (51.8%) were the common symptoms. Aspiration or open drainage was performed in 77 cases (70.0%), and excision was performed in 17 cases(15.5%). Thirty five (31.9%) patients had neurologic sequelae after treatment, and the mortality rate was 11.8%. Factors influencing mortality of brain abscess were mental status and multiple abscesses.CONCLUSION:
Brain abscess is still a critical infectious disease of the central nervous system with high mortality and morbidity in Korea. Active surgical procedures including aspiration, open drainage or excision, as well as antibiotic therapy, are needed for the proper management.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Cardiovascular Disease
/
Congenital and Chromosomal Anomalies
/
Non-migraine Headache
/
Other circulatory Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Otitis Media
/
Parietal Lobe
/
Brain
/
Brain Abscess
/
Central Nervous System
/
Drainage
/
Medical Records
/
Epidemiology
/
Communicable Diseases
/
Retrospective Studies
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2003
Document type:
Article