Association Study between DRD2 Genetic Polymorphisms and Schizophrenia in a Korean Population
Journal of the Korean Society of Biological Psychiatry
; : 53-57, 2012.
Article
in Ko
| WPRIM
| ID: wpr-725111
Responsible library:
WPRO
ABSTRACT
OBJECTIVES: This study was designed to investigate the association between the dopamine D2 receptor (DRD2) genetic polymorphism [TaqIB (rs17294542) and TaqID (rs1800498)] and patients with schizophrenia. METHODS: TaqIB (rs17294542) and TaqID (rs1800498) polymorphism of the DRD2 gene were typed in 100 patients with schizophrenia and 109 normal controls. RESULTS: There were no statistical differences in genotype and allele distribution of TaqIB (rs17294542) and TaqID (rs1800498) genetic polymorphism between patients with schizophrenia and normal controls. CONCLUSIONS: These results suggest that the TaqIB (rs17294542) and TaqID (rs1800498) polymorphisms of the DRD2 gene may not be associated with schizophrenia in the Korean population.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Polymorphism, Genetic
/
Schizophrenia
/
Receptors, Dopamine D2
/
Alleles
/
Genotype
Limits:
Humans
Language:
Ko
Journal:
Journal of the Korean Society of Biological Psychiatry
Year:
2012
Document type:
Article