Usefulness of acoustic radiation force impulse elastography in the differential diagnosis of benign and malignant solid pancreatic lesions
Ultrasonography
; : 26-33, 2014.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-731177
Responsible library:
WPRO
ABSTRACT
PURPOSE:
The aim of this study was to evaluate the tissue stiffness of solid pancreatic lesions by using acoustic radiation force impulse (ARFI) elastography to differentiate benign from malignant pancreatic lesions.METHODS:
ARFI elastography was performed in 26 patients who had 27 focal solid pancreatic lesions, including 8 benign lesions (mass-forming pancreatitis, 5; autoimmune pancreatitis, 3) and 19 malignant lesions (pancreatic adenocarcinoma, 16; metastasis from colorectal cancer, 2; malignant neuroendocrine tumor, 1). On the elastographic images of virtual touch tissue imaging (VTI), the echogenicity of the mass was categorized on a 5-grade scale. On the elastographic image of virtual touch tissue quantification (VTQ), the shear wave velocities (SWVs) of the lesion and surrounding parenchyma were measured.RESULTS:
On the VTI images, the mean echogenicity score of the malignant lesions (3.7+/-1.0) was higher than that of the benign lesions (3.1+/-0.4; P=0.023). On the VTQ images, there were no statistical differences in the mean SWV between the benign (2.4+/-1.1 m/sec) and malignant (3.3+/-1.0 m/sec) lesions (P=0.101). However, the mean SWV difference values between the lesion and background parenchyma of the malignant lesions (1.5+/-0.8 m/sec) were higher than those of the benign lesions (0.4+/-0.3 m/sec; P=0.011).CONCLUSION:
ARFI elastography can determine the relative stiffness between a lesion and the background pancreatic parenchyma using VTI and VTQ, which is helpful in the differentiation between benign and malignant solid pancreatic lesions.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pancreas
/
Pancreatic Neoplasms
/
Pancreatitis
/
Acoustics
/
Colorectal Neoplasms
/
Adenocarcinoma
/
Ultrasonography
/
Neuroendocrine Tumors
/
Diagnosis, Differential
/
Elasticity Imaging Techniques
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Ultrasonography
Year:
2014
Document type:
Article