Response to neuromuscular blockade with rocuronium during general anesthesia in a patient with dermatomyositis: A case report
Anesthesia and Pain Medicine
; : 61-64, 2018.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-739429
Responsible library:
WPRO
ABSTRACT
Dermatomyositis is an idiopathic inflammatory myopathy characterized by skin changes and muscle weakness. Depending on the involvement of various muscles, dermatomyositis can cause aspiration pneumonia, ventilatory impairment, and heart failure. Several reports have documented normal or prolonged neuromuscular blockade following administration of different non-depolarizing neuromuscular blockers in patients with dermatomyositis. We observed delayed onset of blockade and prolonged recovery following administration of 0.6 mg/kg rocuronium in a patient with dermatomyositis. However, when the train-of-four ratio reached 0.3, the patient was administered pyridostigmine and glycopyrrolate, which led to normal response to reversal of rocuronium. The patient was extubated without respiratory complications. The outcomes of this case indicate that response to the usual dosage of muscle relaxants in patients with dermatomyositis might be different from that in patients without this condition. Anesthesiologists should pay attention to preoperative cardiorespiratory evaluation and intraoperative neuromuscular monitoring.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pneumonia, Aspiration
/
Pyridostigmine Bromide
/
Skin
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Muscle Weakness
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Neuromuscular Blockade
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Dermatomyositis
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Neuromuscular Monitoring
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Glycopyrrolate
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Heart Failure
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Anesthesia, General
Limits:
Humans
Language:
English
Journal:
Anesthesia and Pain Medicine
Year:
2018
Document type:
Article