Recurrent Familial Furunculosis Associated with Panton-Valentine Leukocidin-Positive Methicillin-Susceptible Staphylococcus aureus ST1
Pediatric Infection & Vaccine
; : 107-112, 2018.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-741853
Responsible library:
WPRO
ABSTRACT
Staphylococcus aureus is now a major community-acquired pathogen worldwide, notably associated with skin and soft tissue infections. Staphylococci are present in the form of colonizers or environmental contaminants at home and increase the risk of recurrent infection. We are describing recurrent familial furunculosis caused by Panton-Valentine Leukocidin-positive methicillin susceptible S. aureus ST1 in Korea. An infant, his father and mother had furunculosis due to methicillin-sensitive S. aureus (MSSA) infection with identical susceptibility patterns. ST1 accounted for all 3 isolates and they were confirmed of having agr group I. Both sec and seh were detected in all isolates using polymerase chain reaction (PCR) assays, and all isolates contained Panton-Valentine leukocidin (PVL) genes. Risk factors for the household spread of S. aureus include skin conditions and close physical contact among household members. The relationship between S. aureus colonization of household contacts and the occurrence of S. aureus infection should be studied into more detail.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Zoonoses
Database:
WPRIM (Western Pacific)
Main subject:
Skin
/
Staphylococcus
/
Staphylococcus aureus
/
Family Characteristics
/
Polymerase Chain Reaction
/
Risk Factors
/
Colon
/
Soft Tissue Infections
/
Fathers
/
Furunculosis
Type of study:
Etiology study
/
Risk factors
Limits:
Humans
/
Infant
Country/Region as subject:
Asia
Language:
English
Journal:
Pediatric Infection & Vaccine
Year:
2018
Document type:
Article