Research progress of TRIM14 in malignant tumors / 国际肿瘤学杂志

ABSTRACT

Tripartite motif-containing 14 (TRIM14) is a member of tripartite motif family.Regulating innate immune response and affecting cell differentiation are the main physiological functions of TRIM14.It is reported TRIM14 expresses in various tumors such as non-small cell lung cancer,breast cancer,hepatocellular carcinoma,osteosarcoma and oral squamous cell carcinoma.The proliferation,invasion,metastasis,drug resistance of malignant tumors and the prognosis of patients with cancer can be affected via different mechanisms of TRIM14.