Orthogonal experimental study on preparation technology of borneol-β-CD inclusion complex / 国际中医中药杂志

ABSTRACT

Objective To study the optimal preparation of β-cyclodextrin inclusion borneol by saturated aqueous solution. Methods The orthogonal experimental design was used to evaluate the inclusion process using the content of borneol in the inclusion complex as an indicator. Results The optimum inclusion compound technology was β-CD 20 g, the amount of borneol was 2.3 g, the water temperature was 65 ℃, and the stirring speed was 800 r/min. Conclusions This process is simple, stable, and high in inclusion rate. It is suitable for scientific research and industrial application.