Serum allergen-specific IgE in patients with eosinophilic nasal polyps / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To investigate the relationship between airborne allergen and patients with nasal polyps (NP).@*METHOD@#Eighty-three cases of patients with NP were classified into the eosinophilic group(ENP) and non eosinophilic group (nENP) in terms of the EOS count in NP specimen, all patients underwent specific-IgE test with standardized allergens and the results were analyzed.@*RESULT@#The specific-IgE positive rate was 59.26% in ENP group and 23.21% in the nENP group respectively (P < 0.01), and the positive rate of ENP was statistical significance compared with nENP. The dust mite was the most prevalent airborne allergen in ENP group.@*CONCLUSION@#The perennial airborne allergens may play a certain role in the etiology and pathogenesis of NP.