Expression and clinical significance of 6-phosphofructo-1-kinase in nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 393-395, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-749379
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#The aim of this study is to investigate the expression and clinical significance of 6-phosphofructo-1-kinase in nasopharyngeal carcinoma biopsy samples.@*METHOD@#Sixty-one biopsy samples were detected, including 41 tissues samples from patients with nasopharyngeal carcinoma and 20 tissues samples from patients with chronic nasopharyngitis as control group. 6-phosphofructo 1 kinase mRNA expression was detected by RTPCR.@*RESULT@#It was observed that the expression levels of 6 phosphofructo-1-kinase mRNA in nasopharyngeal carcinoma tissues were higher than in the chronic inflammatory tissues. And the expression levels in patients with lymph node metastasis were higher than without lymph nod metastasis.@*CONCLUSION@#6-phosphofructo-1-kinase may be a marker in occurrence and metastasis of nasopharyngeal carcinoma.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
RNA, Messenger
/
Carcinoma
/
Biomarkers, Tumor
/
Nasopharyngeal Neoplasms
/
Phosphofructokinase-1
/
Nasopharyngeal Carcinoma
/
Genetics
/
Lymphatic Metastasis
/
Metabolism
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2014
Document type:
Article