A Cabe of Clozapine-Induced Agranulocytosis / 신경정신의학
Journal of Korean Neuropsychiatric Association
; : 186-193, 1998.
Article
in Ko
| WPRIM
| ID: wpr-75829
Responsible library:
WPRO
ABSTRACT
We report a 20-year-old female patient who developed clozapine-induced agranulocytosis on the 29th day of clozapine treatment. She recovered from the agranulocytosis on the 8th day of progression after treatment with G-CSE, GM-CSF, antibiotics and associated aseptic procedures. The cause of clozapine-induced agranulocytosis is still un known and it is proposed that the dominant gene of major histocompatibility complex region and the reactive metabolites which suppress the myeloid system may be responsible. We recommend that careful attentions such as the selection of patient, evaluation of the risk factors, and the thorough control of CPMS should be paid. If the agranulocytosis happens, it is helpful to consult to the department of medicine immediately.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Attention
/
United Nations
/
Risk Factors
/
Granulocyte-Macrophage Colony-Stimulating Factor
/
Clozapine
/
Agranulocytosis
/
Genes, Dominant
/
Major Histocompatibility Complex
/
Anti-Bacterial Agents
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
Language:
Ko
Journal:
Journal of Korean Neuropsychiatric Association
Year:
1998
Document type:
Article